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科研情况： |
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江苏省植物药深加工工程研究中心主任、国家中医药管理局中药制剂三级实验室主任、江苏省中药资源产业化过程协同创新中心方向带头人。江苏省高校“青蓝工程”优秀教学团队负责人，江苏省“333高层次人才培养工程”中青年科技领军人才，江苏省“六大人才高峰”高层次人才，江苏省“青蓝工程”中青年学术带头人、优秀青年骨干教师。从事中药制药分离原理及中药资源循环利用研究。已发表论文180余篇，主编、副主编专著3部，主编、副主编行业规划教材3部。获授权专利28项；药学主持获得中药新药临床批件5件、主要参与获得中药新药证书3件，均已实现转化。
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代表性论文： |
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1. Ping-Yuan Ge, Shu-Yue Qu, Sai-Jia Ni, Zeng-Ying Yao, Yi-Yu Qi, Xin Zhao,Rui Guo, Nian-Yun Yang, Qichun Zhang*,Hua-Xu Zhu*.Berberine ameliorates depression-like behaviors in mice exposed to CUMS by activating TPH1 and inhibiting IDO1 associated with tryptophan metabolism.Phytotherapy Research, 2022:DOI: 10.1002/ptr.7616. 2.Hongbo Liu, Xingbao Tao,Huaxu Zhu*, Zhishu Tang*, Sining Xu, Bo Li, Zhongxing Song, Linmei Pan, Yue Zhang, Jinao Duan. Effect of operation mode on membrane fouling from traditional Chinese medicine water extracts.Journal of Water Process Engineering,2022 (48): 102943. 3.Zhang Y, Huang M C, Wang Q S, Zhang X L, Peng J, Zhang Y, Wu Q L, Duan J A, Mao X J, Tang Z S, Li B*, Zhu H X*. Insights into the penetration of PhACs in TCM during ultrafiltration: Effects of fouling mechanisms and intermolecular interactions [J].Separation and Purification Technology,2022 (295): 121205. 4. Yiyu Qi, Xia Heng, Zengying Yao, Shuyue Qu, Pingyuan Ge, Xin Zhao, Saijia Ni, Rui Guo, Nianyun Yang, Qichun Zhang*,Hua-Xu Zhu*.Involvement of Huanglian Jiedu Decoction on Microglia with Abnormal Sphingolipid Metabolism in Alzheimer’s Disease.Drug Design, Development and Therapy, 2022(16): 931-950. 5.Hong-Bo Liu, Bo Li#, Li-Wei Guo,Lin-Mei Pan,Hua-Xu Zhu*, Zhi-Shu Tang*, Wei-Hong Xing, Yuan-Yuan Cai, Jin-Ao Duan, Mei Wang, Si-Ning Xu, Xing-Bao Tao. Current and Future Use of Membrane Technology in the Traditional Chinese Medicine Industry.Separation & Purification Reviews, 2021: 1995875, 1~19. 6. Ping-Yuan Ge, Yi-Yu Qi, Shu-Yue Qu, Xin Zhao, Sai-Jia Ni, Zeng-Ying Yao, Rui Guo, Nian-Yun Yang, Qi-Chun Zhang*,Hua-Xu Zhu*. Potential Mechanism ofS. baicalensison Lipid Metabolism Explored via Network Pharmacology and Untargeted Lipidomics.Drug Design, Development and Therapy, 2021(15): 1915-1930. 7. Shu-Yue Qu, Xiao-Yue Li, Xia Heng, Yi-Yu Qi, Ping-Yuan Ge, Sai-Jia Ni, Zeng-Ying Yao, Rui Guo, Nian-Yun Yang, Yi Cao, Qi-Chun Zhang*,Hua-Xu Zhu*. Analysis of antidepressant activity of Huang-Lian Jie-Du decoction through network pharmacology and metabolomics.Frontiers in Pharmacology, 2021: DOI:10.3389/fphar.2021.619288. 8. Yu-Mei Hu, Wen-Jun Liu, Meng-Xuan Li, Hai-Bo Li, Tao Jiang, Ning-Bo Cheng, Wen-Zhe Huang, Zhen-Zhong Wang,Hua-Xu Zhu*, Wei Xiao*. Two new labdane diterpenoids from aerial parts of Leonurus japonicus and their anti-inflammatory activity.Natural Product Research, 2018, DOI: 10.1080/14786419.2018.1455040. 9.朱华旭，唐志书，李博，刘红波，潘林梅，付廷明，段金廒，邢卫红*，高从堦*.中药制药废水膜法零排放的特种膜材料设计关键技术与实现途径探讨.南京中医药大学学报（自然科学版），2020，36(5)：579-583. 10.朱华旭，唐志书，郭立玮，刘红波，潘林梅，李博，邢卫红，高从堦*.中药挥发油膜法高效富集的油水分离原理研究及其新型膜分离过程的探索实践.南京中医药大学学报（自然科学版），2019，35(5)：491-495.
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荣誉奖励： |
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1.江苏省科技进步二等奖; 2.中华中医药学会科学技术一等奖、二等奖等奖励6项; 3.江苏省教学成果二等奖2项。
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社会兼职： |
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1.全国专业标准化技术委员会委员（SAC/TC168）; 2.中国颗粒学会青年理事; 3.中国中药协会中药资源循环利用专委会副主任委员; 4.江苏省颗粒学会副理事长、生物医药专业委员会主任委员。
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